Makoto Naoi Selected Research

Neuroinflammatory Diseases

1/2022

Disease-modifying treatment of Parkinson's disease by phytochemicals: targeting multiple pathogenic factors.

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Makoto Naoi Research Topics

Disease

21	Parkinson Disease (Parkinson's Disease) 01/2022 - 06/2002
16	Neurodegenerative Diseases (Neurodegenerative Disease) 11/2018 - 05/2004
10	Neuroblastoma 11/2018 - 03/2002
7	Alzheimer Disease (Alzheimer's Disease) 11/2018 - 05/2004
5	Mitochondrial Diseases (Mitochondrial Disease) 01/2020 - 01/2002
2	Inflammation (Inflammations) 01/2020 - 01/2010
2	Disease Progression 01/2020 - 01/2010
2	Glioblastoma (Glioblastoma Multiforme) 11/2018 - 01/2017
1	Neuroinflammatory Diseases 01/2022
1	Prodromal Symptoms 01/2020
1	Motor Neuron Disease (Primary Lateral Sclerosis) 01/2020
1	Mental Disorders (Mental Disorder) 11/2018
1	Depressive Disorder (Melancholia) 01/2018
1	Neoplasms (Cancer) 01/2017
1	Inborn Genetic Diseases (Disease, Hereditary) 02/2016
1	Pheochromocytoma 07/2009
1	Lewy Body Disease (Lewy Body Dementia) 05/2003
1	Neuropathy ataxia and retinitis pigmentosa 01/2002
1	Leigh Disease (Leigh's Disease) 01/2002

Drug/Important Bio-Agent (IBA)

13	Monoamine Oxidase (MAO)IBA 11/2018 - 01/2005
12	rasagiline (Azilect)FDA Link 01/2020 - 06/2002
8	Nerve Growth Factors (Neurotrophins)IBA 01/2022 - 08/2009
8	Selegiline (E250)FDA LinkGeneric 01/2020 - 08/2009
6	Proteins (Proteins, Gene)FDA Link 01/2022 - 11/2003
6	NeurotoxinsIBA 03/2013 - 03/2002
5	Neuroprotective AgentsIBA 01/2022 - 05/2004
5	salsolineIBA 05/2004 - 08/2002
4	EnzymesIBA 02/2016 - 01/2002
3	SynucleinsIBA 01/2022 - 05/2018
3	PhytochemicalsIBA 01/2022 - 01/2017
3	Dopamine (Intropin)FDA LinkGeneric 01/2020 - 09/2002
3	Monoamine Oxidase Inhibitors (Monoamine Oxidase Inhibitor)IBA 01/2017 - 01/2010
2	AntioxidantsIBA 01/2022 - 01/2017
2	Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric 11/2018 - 09/2004
2	Neurotransmitter Agents (Neurotransmitter)IBA 01/2018 - 05/2004
2	Messenger RNA (mRNA)IBA 02/2016 - 05/2004
2	Glial Cell Line-Derived Neurotrophic Factor (GDNF)IBA 01/2013 - 05/2004
2	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2012 - 01/2011
2	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2010 - 11/2003
2	neuromelaninIBA 11/2009 - 06/2008
2	NitrogenIBA 01/2005 - 11/2003
2	RotenoneIBA 01/2005 - 11/2003
2	Acrolein (Aqualin)IBA 01/2005 - 11/2003
2	Oxygen (Dioxygen)IBA 01/2005 - 11/2003
2	Pharmaceutical PreparationsIBA 05/2004 - 06/2002
1	LipidsIBA 05/2018
1	Docosahexaenoic AcidsIBA 05/2018
1	Indicators and Reagents (Reagents)IBA 05/2018
1	Lysine (L-Lysine)FDA Link 05/2018
1	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA 05/2018
1	Norepinephrine (Noradrenaline)FDA LinkGeneric 01/2018
1	Serotonin (5 Hydroxytryptamine)IBA 01/2018
1	Lipid PeroxidesIBA 01/2014
1	Brain-Derived Neurotrophic Factor (BDNF)IBA 01/2013
1	1- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA 01/2011
1	sesaminIBA 07/2009
1	Biogenic Amines (Biogenic Amine)IBA 01/2005
1	AldehydesIBA 01/2005
1	Caspase 3 (Caspase-3)IBA 09/2004
1	LigninIBA 09/2004
1	Caspase 9IBA 09/2004
1	Caspase 8 (Caspase-8)IBA 09/2004
1	N-propargylIBA 05/2004
1	NF-kappa B (NF-kB)IBA 05/2004
1	Transcription Factors (Transcription Factor)IBA 05/2004
1	salsolinol N-methyltransferaseIBA 01/2004
1	AntibodiesIBA 11/2003
1	dityrosineIBA 11/2003
1	Cholinesterases (Cholinesterase)IBA 05/2003
1	CarbamatesIBA 05/2003
1	salsolinolIBA 09/2002
1	MethyltransferasesIBA 09/2002
1	Cytochromes c (Cytochrome c)IBA 08/2002
1	Oxidopamine (6 Hydroxydopamine)IBA 03/2002
1	DNA Restriction Enzymes (Restriction Endonuclease)IBA 01/2002
1	Protons (Proton)IBA 01/2002

Therapy/Procedure

8	Therapeutics 01/2020 - 09/2002